2 questions on immunity involving chicken pox and flu?!) The chicken pox virus needs 2 to 3 days to establish a thriving infection. The antibody response takes 5 to 7 days to become fully effective. What might happen if a person was infected by the chicken pox virus but had no macrophages?
2) Why do most people get chicken pox just once, but they get the flu again and again?
Looking for semi lenghy answers to give best answer to
Answer by Jay M
1. Macrophages are important in surviving influenza infection mainly due to their role as APCs. Macrophages are not the only APCs that can initiate an immune response against influenza. There are also dendritic cells and B cells that do the same thing.
2. There is currently only one serotype of chickenpox virus circulating in humans. Infection results in immunity to the only virus that is out there. In addition, you come in contact with chickenpox on a fairly regular basis just by interacting with others. These secondary exposures continually boost your immunity, and so it is life-long.
Influenza viruses, on the other hand, mutate rapidly from year to year. Infection with influenza this year may or may not protect you against next year's virus. It just depends on how much the virus changes during that season. This is not predictable, but must be continually monitored.
Get the facts on the chickenpox vaccine, treatment, causes (varicella zoster virus, VZV), symptoms and signs (itchy, red rash).
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